The Usage of a Locomotive Tractive Power in the Different Operating Modes and the Efficiency Control_Crimson Publisher

The Usage of a Locomotive Tractive Power in the Different Operating Modes and the Efficiency Control by Alexander Jr Zarifyan in Crimson Publishers: Open Journal of Civil Engineering

A significant share of energy consumed by rail systems is used to move the trains [1]. In our opinion, it is necessary to study carefully the efficiency of freight electric locomotives in different modes of operation.

Modern freight electric locomotives have a multi-engine electric traction drive (up to 16 traction motors) with tractive effort control system on each axle. Therefore, the approach of the Scalable Power Control Technology [2,3], which regulates the quantity of locomotive traction motors (TM) in traction mode, seems quite reasonable. In our case, if full locomotive tractive power is not needed within operation, the redundant motors must be automatically switched off [4,5]. But when additional tractive power is required, the locomotive must use sufficient number of motors.

https://crimsonpublishers.com/acet/fulltext/ACET.000529.php

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Soil Improvement for Present and Future: Crimson Publishers

Soil Improvement for Present and Future by Shulbhi Verma* in Journal of Biotechnology & Bioresearch - Crimson Publishers: Bioresearch

Soil is the nonrenewable, finite natural asset for the earth and the living beings on the blue planet. Today 9 billion people required quality of food for better health and long survival. Pressure increased on soil in comparison to the past due to increase in population for more and nutritious food production. The safe ecosystem with food production makes challenge more difficult. There are many factors responsible for the safe ecosystem among that healthy soil makes remarkable contribution in the development of plant and could be considered very essential factor. Our main concern should be for the protection of soil physical, chemical and biological property with production. During last two decades food crops decreased, and nonfood crop cultivation increased. Farmers adopted intensive cropping patterns of commercial crops in place of more balance cereal legumes rotation. Intensive cultivation leads to removal large quantities of nutrition from the soil which resists to in loss of soil fertility. The farmers maintain productivity of soil by applying chemical fertilizer instead of organic fertilizer. Such cropping system makes the soil condition very pitiful because it creates disturbance in the soil physical, chemical and biological condition

https://crimsonpublishers.com/jbb/pdf/JBB.000513.pdf

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Application of Queuing Theory to Larfarge Cement Transportation System for Truck/Loader Optimazation-Crimson Publishers

Application of Queuing Theory to Larfarge Cement Transportation System for Truck/Loader Optimazation by Afeni Thomas B in Aspects in Mining & Mineral Science: Crimson Publishers-journal of Mining& Mineral Science

Surface mining is the most common mining method worldwide; open pit mining accounts for more than 60% of all surface output. This project uses queuing technique to optimize the transportation at Lafarge WAPCO (Sagamu plant) Nigeria. Queuing theory was developed to model systems that provide service for randomly arising demands and predict the behaviour of such systems. Time of arrival at excavator area (hr/min/sec), time of first load by excavator into the truck (hr/min/sec), number of loads, time of departure from the excavator (hr/min/sec) and time taken to load trucks gotten from the Lafarge (Sagamu plant) was analysed to develop a model M/M/1: FCFS/∞/∞, based on the assumption of single channel and single server with infinite number of queues. The model was used to calculate the arrival rate, service rate and number of server which at the end of it gives 7turcks/hour, 21trucks/hour and 1loader respectively. @risk software was used to fit both service and inter-arrival into exponential distribution. The result shows that as the size of the haulage truck being used increases, shovel productivity increases and truck productivity decreases. An effective number of trucks must be chosen that will effectively utilize idle time, increase productivity and reduce cost of production to the barest minimum. The idle time gotten is 66.6%; this indicates that an additional 8 to 9 trucks can be added to the company truck fleet to make use of the idle time; since time translate to cost.

https://crimsonpublishers.com/amms/fulltext/AMMS.000528.php

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Advances in The Therapy of Depression: Crimson Publishers

Advances in The Therapy of Depression by Ghassan Haddad in Techniques in Neurosurgery & Neurology: Crimson Publishers_Journal of Neurology Neurosurgery and Psychiatry

Depression is one of the most common serious medical and psychiatric disorders, with greater than 200 million adults worldwide suffering from major depressive disorder (MDD) at any given time, according to a 2003 report by the World Health Organization titled Investing in Mental Health. According to the U.S. National Comorbidity Survey Replication published in 2007, more than 16 million adults in the United States, which represents approximately 6.7% of itsentire adult population, will suffer from MDD in a 12-month period. The quest to come up with a superior antidepressant is in full effect among biotech and pharmaceutical companies. Although there are some companies that are still tweaking various formulations of serotonergic, noradrenergic, and dopaminergic substances i.e. triple reuptake inhibitors others are thinking outside the box.

https://crimsonpublishers.com/tnn/fulltext/TNN.000526.php

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Study of Methanolic Extract of Leaves Calotropis gigantea (L.) As an Anti-Solar- Crimson Publishers

Study of Methanolic Extract of Leaves Calotropis gigantea (L.) As an Anti-Solar by Gharge Varsha Gajanan in Advances in Complementary & Alternative Medicine- Crimson Publishers: Journal of Alternative and Complementary Medicine

Objective: The present study aimed at the phytochemical examination and anti-solar activity of Calotropis gigantea L. (leaf) methonolic extract has more flavonoid content based on this chemical substance photo protective activity was evaluated using UV visible spectrophotometry, where the method is diffused transmittance and the range of UV-visible about 200-400nm.

Methods: The pulverized dried Calotropis gigantea L. leaves were extracted with Methanol using soxhlet apparatus. Methanol extract were filtered & evaporated to dryness. The photo protective activity was evaluated by using UV visible spectrophotometry, where the method it is diffused transmittance and the range of UV-visible about 200-400nm for absorption.

Results: The UV scanning absorption spectra of the extract showed very strong absorption at 0.273A with max at 397nm.

Conclusion: The extract has an ability to absorb in the entire UV range.

https://crimsonpublishers.com/acam/fulltext/ACAM.000518.php

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Perspectives of Complement System in Inflammatory Diseases- Crimson Publishers

Perspectives of Complement System in Inflammatory Diseases by Lalit M Srivastava* in Advances in Complementary & Alternative medicine-Crimson Publishers: Journal of Traditional and Complementary Medicine

The Complement System provides a rapid and efficient means to protect the host from invasive microorganisms. Due to its diverse biological activities, complement is the major mediator of inflammation, a natural response to the host tissue to any injury. Evidences are available to show that complement significantly contributes to the regulation of immune response. Furthermore, the effector functions arising from complement activation carry the potential for harming the host by directly or indirectly mediating inflammatory tissue destruction. Inappropriate or excessive activation of the complement system can lead to harmful, potentially life-threatening consequences due to severe inflammatory destruction. Genetic complement deficiencies or complement depletion have been found to be beneficial in reducing tissue injury of severe complement dependent inflammation.

https://crimsonpublishers.com/acam/fulltext/ACAM.000517.php

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Common Etiology of Foreign Body Ingestion_ Crimson Publishers

Common Etiology of Foreign Body Ingestion by Adnan Qureshi*, Joanne Cunningham and Sobia Naz in Crimson Publishers: Surgical Medicine

Background: The aim of this study was to look at the demography, sites of insertion, most common causes of foreign body ingestion and the procedures used for retrieval of these foreign bodies (FB). We also looked at length of stay and common a mental health diagnosis for patients admitted with FB ingestion.

Material & Method: This was a retrospective analysis of four years data from January 2014 to January 2018 at Northampton general Hospital. The data was collected using the hospital electronic record system. All patients admitted under surgical subspecialties and gastroenterology was included. Children with a genital FB were excluded from the study. The number of admissions for each patient was recorded. Patients were divided into accidental and mental health illness (MHI) groups.

Result: A total of 146 patients were admitted with FB diagnosis. 57% (84) were in the accidental group and 43% (63) were in the MHI group. In the accidental group 70% (54) were under the age of 16 years, the most common cause was inorganic FB and the most common site was an ENT. While in adults most common site in accidental FB was oesophagus and the food bolus was the commonest cause. In the MHI group 63 patients had 257 admissions episodes. The mean age was 25±21 years. Female sex and younger age i.e early adulthood were at a higher risk for FB ingestion. Abdominal x-ray was the most common investigation. Mean length of stay was 3±2 days. Endoscopic retrieval was successful in 85% of patients. Most common mental health diagnosis was deliberate self-harm (DSH) 40%.

Conclusion: Younger age group, female sex and patients with history of DSH are at a higher risk of FB ingestion and recurrent presentation. Early recognition of high-risk patients and prompt psychiatric help can minimise the recurrent presentation of these patients. Minimally invasive techniques like endoscopic retrieval of FB should be first choice.

https://crimsonpublishers.com/smoaj/fulltext/SMOAJ.000525.php

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Macular Abnormality after Successful Surgery for Idiopathic Macular Hole Assessed Using Optical Coherence Tomography | Crimson Publishers

Macular Abnormality after Successful Surgery for Idiopathic Macular Hole Assessed Using Optical Coherence Tomography by Nazimul Hussain in Medical & Surgical Ophthalmology Research

Purpose: Macular changes following Internal Limiting Membrane peeling after successful Macular hole closure using optical coherence tomography.

Methods: 5 eyes of 5 patients were included in the study. The inclusion criteria were idiopathic full thickness macular hole and completed at least 6 months follow up. All patients underwent optical coherence tomography assessment before and after surgery until 6 months. Macular thickness and morphology map was analyzed before and after surgery.

Results: There were 3 males and 2 females. The age range from 45 to 59 years. Conspicuous irregular surface of the inner retina on Optical Coherence Tomography surface topography was evident in all eyes at 6 months. This was also associated with downward slope of the temporal macula seen on surface topography. There was trend towards decrease in subfield thickness especially in the T1, S1, I1 and N1 6 months after surgery. The average decrease was -60.4 microns in T1, -20.4 microns in S1, -13.0 microns in I1 and -23.4 microns in N1.

Conclusion: In this small case series brilliant blue assisted ILM peeling after successful macular whole closure showed evidence of decrease in macular thickness in all first subfield quadrant and downward slope of the temporal macula as well as conspicuous irregularity of the inner retina.

https://crimsonpublishers.com/msor/fulltext/MSOR.000517.php

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Broadening the Spectrum of Diffusion Weighted Imaging to Evaluate Marrow Pathologies-Crimson Publishers

Broadening the Spectrum of Diffusion Weighted Imaging to Evaluate Marrow Pathologies by Meena GL in Crimson Publishers: Bone disease

Objectives: To evaluate the signal characteristics of normal adult bone marrow in whole-body diffusion-weighted (DW) images (WB-DWI), to correlate these characteristics with age and gender, and to determine the causes of these phenomena.

Material and Methods: Ninety-eight healthy volunteers underwent WB-DWI (b=0 and 800s/mm2). Two radiologists visually evaluated the signal characteristics of bone marrow in DW images separately. One radiologist measured the apparent diffusion coefficient (ADC) of the thoracic and lumbar vertebrae, bilateral femur (including head, neck, and proximal and distal femoral shaft), bilateral humeral head, ilium, and scapula. The signal characteristics of normal bone marrow were analyzed.

Results: The visual evaluation results of DW images indicated that hyperintensity of bone marrow was more frequently seen in women aged 21-50 years (68.4%) than in men aged 21-50 years (3.3%) (P <0.001), men aged 51-81 years (5.9%) (P<0.001), and women aged 51-81 years (15.4%) (P=0.001). However, no statistically significant difference was found between men and women aged 51-81 years (P=0.565). The ADC of bone marrow was significantly higher in women than in men aged 21-50 years. Bone marrow ADC showed significant negative correlation with age in women but

not in men.

Conclusion: The signal intensity of bone marrow varies with age and gender in DW images. ADC and the T2 shine through effect contributed to the bone marrow signal intensity in DW images, and the latter effect may predominate.

https://crimsonpublishers.com/rabs/fulltext/RABS.000509.php

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Bones, Arthritis and the Body’s Water-Some Practical Suggestions: Crimson Publishers

Bones, Arthritis and the Body’s Water-Some Practical Suggestions by Maria Kuman* in Crimson Publishers: Bone Marrow Research

Our body is mostly water. How this relates to bones and arthritis? Speaking about the amount of water in the body, we should acknowledge its decline with aging. According to Russian studies [1], the amount of water in the fetus is 95%, in the baby- 92%, and it constantly decreases. Between age 20 and 30 the amount of water in the body is 70%, between age 40 and 50 it is 50% (this is when the wrinkles appear). After the age of 70, the amount of water in the body drops down to 30%. This is when the bones become brittle because there is no enough water in them to keep them elastic [1].

The bones have tiny canals filled with structured water. This keeps the bones elastic. When after the age of 70 the amount of water in the body (including bones) drops down to 30%, the bones become brittle. That is why it is so dangerous for the elderly to fall because the chances to break a bone at the fall are high. Hormones rule the amount of water in the body. With the aging as the number of hormones decline, and so does the amount of water in the body. How does arthritis relate to water? Arthritis is more frequent among elderly when the amount of water in the body decreases, but the toxins deposited in the joints play a major role in arthritis

https://crimsonpublishers.com/rabs/fulltext/RABS.000510.php

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A Secreted Protein in the Wnt Signaling Pathway-R-Spondin3: A Mini-Review_Crimson Publishers

Secreted Protein in the Wnt Signaling Pathway-R-Spondin3: A Mini-Review by Qing Yang in Significances of Bioengineering & Biosciences: Crimson Publishers_American Journal of Bioscience and Bioengineering

R-spondins (Roof plate-specific Spondins, RSPOs) are secreted proteins, which act as activators of Wnt/β-catenin signaling and play roles in cell proliferation and differentiation, embryonic development, vasculogenesis as well as many human diseases. R-spondin3 (RSPO3) is a member of RSPOs family, containing two adjacent cysteine-rich furin-like domains, which act as an agonist in Wnt signaling. In this mini-review, we discuss and classify recent progress in understanding the protein functions of RSPO3 in embryonic development, vasculogenesis, and its role in cancers.

https://crimsonpublishers.com/sbb/fulltext/SBB.000518.php

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PEX12 Novel Mutation: A Case Report on Iranian Girl with Childhood Onset Peroxisomal Disorder: Pseudo ALD?: Crimson Publishers

PEX12 Novel Mutation: A Case Report on Iranian Girl with Childhood Onset Peroxisomal Disorder: Pseudo ALD? by Tabarestani S in Research in Pediatrics & Neonatology: Peroxisomal Disorder

Objective: To report a 7 years old girl with genetic and biochemical characteristics of zellweger spectrum disorder who presented with phenotype and neuro imaging findings of adrenoleukodystrophy.

Methods: Target gene sequencing was performed by using a custom designed panel for this patient with focused mutation analysis on 16 peroxisomal genes included in the panel. Sanger sequencing was used to confirm the identified mutation.

Results: This patient was homozygote for a missense mutation in exon 2 of the PEX 12 gene; c.541T>G (p.Tyr181Asp) which is a conserved residue in the N-terminal region crucial for localization to peroxisomes. Her parents and healthy sister were also found to have the same heterozygote mutation.

Conclusion: We suggest that PEX 12 gene mutations with a milder phenotype may be a potential candidate for posterior dominant leukodystrophy of childhood resembling X-linked ALD. This is entitled to pseudo- ALD and may be a diagnostic possibility in patients who develop ALD phenotype and neuroimaging particularly, in girls.

https://crimsonpublishers.com/rpn/fulltext/RPN.000524.php

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Decompression Haematuria from Upper Urinary Tract: A Rare Complication_Crimson Publishers

Decompression Haematuria from Upper Urinary Tract: A Rare Complication by
Praveen Pushkar* in Experimental Techniques in Urology & Nephrology: Crimson Publishers_Asian Journal of Urology

In cases of chronic urinary retention, post decompression diuresis and haematuria are well known complications. Majority of cases of decompression haematuria resolves spontaneously. Rarely haematuria is so much that blood transfusion is required. In all the cases reported in literature haematuria occurs as generalized oozing from bladder mucosa after decompression. In the case described below there was isolated bleeding from both renal pelvis rather than bladder mucosa which resulted in obstructive renal failure.

https://crimsonpublishers.com/etun/fulltext/ETUN.000542.php

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A Secreted Protein in the Wnt Signaling Pathway-R-Spondin3: A Mini-Review_Crimson Publishers

Secreted Protein in the Wnt Signaling Pathway-R-Spondin3: A Mini-Review by Qing Yang in Significances of Bioengineering & Biosciences: Crimson Publishers_American Journal of Bioscience and Bioengineering

R-spondins (Roof plate-specific Spondins, RSPOs) are secreted proteins, which act as activators of Wnt/β-catenin signaling and play roles in cell proliferation and differentiation, embryonic development, vasculogenesis as well as many human diseases. R-spondin3 (RSPO3) is a member of RSPOs family, containing two adjacent cysteine-rich furin-like domains, which act as an agonist in Wnt signaling. In this mini-review, we discuss and classify recent progress in understanding the protein functions of RSPO3 in embryonic development, vasculogenesis, and its role in cancers.

https://crimsonpublishers.com/sbb/fulltext/SBB.000518.php

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Macular Abnormality after Successful Surgery for Idiopathic Macular Hole Assessed Using Optical Coherence Tomography | Crimson Publishers

Macular Abnormality after Successful Surgery for Idiopathic Macular Hole Assessed Using Optical Coherence Tomography by Nazimul Hussain in Medical & Surgical Ophthalmology Research

Purpose: Macular changes following Internal Limiting Membrane peeling after successful Macular hole closure using optical coherence tomography.

Methods: 5 eyes of 5 patients were included in the study. The inclusion criteria were idiopathic full thickness macular hole and completed at least 6 months follow up. All patients underwent optical coherence tomography assessment before and after surgery until 6 months. Macular thickness and morphology map was analyzed before and after surgery.

Results: There were 3 males and 2 females. The age range from 45 to 59 years. Conspicuous irregular surface of the inner retina on Optical Coherence Tomography surface topography was evident in all eyes at 6 months. This was also associated with downward slope of the temporal macula seen on surface topography. There was trend towards decrease in subfield thickness especially in the T1, S1, I1 and N1 6 months after surgery. The average decrease was -60.4 microns in T1, -20.4 microns in S1, -13.0 microns in I1 and -23.4 microns in N1.

Conclusion: In this small case series brilliant blue assisted ILM peeling after successful macular whole closure showed evidence of decrease in macular thickness in all first subfield quadrant and downward slope of the temporal macula as well as conspicuous irregularity of the inner retina.

https://crimsonpublishers.com/msor/fulltext/MSOR.000517.php

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Complete Khoya Replacement in Mango Burfi to Increase Shelf Life: A Case Study: The Journal of Poultry Science: Crimson Publishers

Complete Khoya Replacement in Mango Burfi to Increase Shelf Life: A Case Study by Smita Lele*, Tripti Pandey and Shanooba PM in Crimson Publishers: The Journal of Poultry Science

Khoya is a heat coagulated partially dehydrated whole milk product obtained by heating, evaporation & desiccation at atmospheric pressure. The main reaction in the preparation of khoya is the heat denaturation and coagulation of milk proteins. Most of the albumins & globulins are rapidly denatured, the protective properties of the other colloids are destroyed during boiling and the process is accelerated by incorporation of air seen as frothing by constant stirring or container rotation. Albumin and globulins are coagulated below 100 °C, while casein is coagulated above 100 °C. The factors that influence the heat coagulation are temperature and hold up time, concentration of casein, acidity of milk and salt balance [1].

https://www.crimsonpublishers.com/apdv/fulltext/APDV.000524.php

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Ageing and Health Services Use in Israel- Crimson Publishers

Ageing and Health Services Use in Israel by Ariela Lowenstein in Health Services

Israel, as many other countries, must cope with issues that arise from demographic changes that are expressed both in the size and composition of the population. One of the prominent changes is in the age-structure of the society, which is especially influenced by the ageing of the population. Israel's population consists of 12.8% Jewish elders and 4.4% Arab elders. However, the proportion of disabled Jewish elders is 16% compared with 31% among Arab elders [1]. Disability leads to loss of independence, increases consumption of health services, and raises the cost of medical treatments. Among minorities, lower rates in Health Services use were found, since cultural differences are often not considered. Lack of sensitivity towards minority needs may lead to a gap between potential consumers and existing services [2-6].

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https://crimsonpublishers.com/ggs/fulltext/GGS.000536.php