Cast Metal Occlusal Surface: A Case Report_ Crimson Publishers

 Cast Metal Occlusal Surface: A Case Report by Jieun Lee* in Modern Research in Dentistry_ Dentistry Open Access Journals

 

Abstract

A 69-year-old male patient reported to the UTHealth Prosthodontics with the chief complaint of decreased chewing efficiency and the instability with continuous use of his dentures. He was concerned with the functional efficiency of the dentures and not so much about esthetics. The patient was found to have a completely edentulous maxilla with a residual ridge morphology of minimal buccal vestibule and reduced hamular notch. The mandible had one root tip with a reduced residual bone height. The maxillomandibular relationship was Class III. Pt had a history of radiation in the head region with skin cancer of BCC, SCC, and Melanoma since 2008. Frequent attrition of the teeth may either be due to selfinduced excessive chewing. Treatment options offered

(1) denture or implant supported overdenture,

(2) denture or implant supported overdenture with metal occlusal surface, and

(3) implant supported fixed prosthesis

https://crimsonpublishers.com/mrd/fulltext/MRD.000602.php

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Protection of Children from Sexual Violation: Adequacy of the Contemporary Legal Framework in Sri Lanka_ Crimson Publishers

 Protection of Children from Sexual Violation: Adequacy of the Contemporary Legal Framework in Sri Lanka by M A D S J S Niriella* in Forensic Science & Addiction Research_ International Journal of Forensic Sciences

 

 

Abstract
It is often stated that children are the soul and the future of a nation. Protection of children is one of the main responsibilities of adults today. Children in Sri Lanka are vulnerable to sexual violence than other forms of violence. Sexual violence against children has become a social issue in the country. Children are prey for sexual violence due to their tender age, immaturity and dependency. They are subjected to sexual violence both in and outside of their home. In many instances, the perpetrators are known to the child victim. According to the National Child Protection Authority (NCPA) records, the total number of sexual violence cases against children has increased in the recent past. There is no doubt that children should have a right to protection from sexual violence. This protection can be ensured initially through prevention by adjusting socio-economy set up and where sexual violence has already committed, putting an end to impunity as well as providing assistance to the victimized child. A strong legal framework is utmost important in this regard. The purpose of the paper is to critically evaluate the efficacy of the existing laws and enforce mechanisms in Sri Lanka against child sexual violence. The qualitative research method is adopted, engaging in a desk review referring to the legislations in this regard

https://crimsonpublishers.com/fsar/fulltext/FSAR.000561.php

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Efficacy of Silk Fibroin Based Bio-Ink in 3D Printing for Tissue Engineering_ Crimson Publishers

 Efficacy of Silk Fibroin Based Bio-Ink in 3D Printing for Tissue Engineering by Utibe Udonwa* in Trends in Textile Engineering & Fashion Technology_ Textile Science Engineering Journal

 

Abstract

Today, countless peoples are suffering and dying from various diseases and one of the reason being the non-compatibility and failure of life saving drugs. In fact 90 percent of the new drug that are tested in labs, on animals trials which are promised to cure the problems actually fail in certain humans. Sometimes, the drug failures during human trials are tragic enough to result in rapid multiple organ failures making the human tester incapable from leading his/her normal lifestyle [1]. The drug that demonstrated its ability to cure in the laboratories may not work same on all people as each human body is unique. This poses to be a major challenge for the drug manufacturers whose significant point of concern would be to develop safe and effective drug which is a risky, time consuming and highly expensive process in reality. In finding solutions to avoid such devastating drug failures and detrimental side effects on human trials, engineering and biotechnologists have come forward to work on developing human tissues outside the body and test the drugs on these tissues. As each individual are different from one another, the tissues developed form the body cells would be unique and testing the drugs on such tissues would accurately determine its safety, compatibility and effectiveness prior to human trials [2]. This can ease the process of drug development by reducing our reliance in animal trials and further increasing the acceptance rates with almost zero chance of rejection, ultimately ending up with better, safer and cheaper drugs.

https://crimsonpublishers.com/tteft/fulltext/TTEFT.000561.php

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Histopathological Analysis of Cerebellum Layers in Rats Treated With Extract of Trichosanthes cucumerina: Neuroprotective Functions_ Crimson Publishers

 Histopathological Analysis of Cerebellum Layers in Rats Treated With Extract of Trichosanthes cucumerina: Neuroprotective Functions by Utibe Udonwa* in Advances in Complementary & Alternative medicine_ Journal of Alternative and Complementary Medicine

 

Abstract
Herbal medicine provides neuroprotective functions for different brain disorders, and Trichosanthes cucumerina leaf extracts may provide neuroprotective function on the cerebellum. Evaluation of the neuroprotective potential of Trichosanthes cucumerina (TC) on the cerebellum is carried out. A total of thirty-two (32) adult rats with an average weight of 200g are being used to determine the effect of methanolic extract of Trichosanthes cucumerina leaf on the cerebellum for a period of twenty-eight (28) days. The rats are divided into 4 groups (A-D) with eight rats in each group. Group A animals receive feed and distilled water and serve as control. The animals in group B, C and group D receive 200mg/kgBW, 400mg/kgBW and 600mg/kgBW of methanolic extract of Trichosanthes cucumerina leaf respectively. 24hours after the last administration of the leaf extract, the animals are sacrificed using chloroform inhalation method. The cerebellum is harvested and fixed in 10% formalin. After fixation, the animals are passed through several stages of tissue processing which comprises dehydration, wax impregnation, embedding and sectioning. The sections are taken at 5μ and haematoxylin and eosin staining method is employed for the histological demonstration of the cerebellum. Microscopy and histochemical data of methanolic extract of T. cucumerina leaf show no adverse histopathological change in cerebellum of all treated groups of rats as they retain their normal cytoarchitecture when compared to the control group. The presence of biologically active phytochemicals including Cucurbitacin in Trichosanthes cucumerina may provide neuroprotective functions especially since the dosage given in the different treatments probably crossed the blood brain barrier and did not produce any pathological effect

https://crimsonpublishers.com/acam/fulltext/ACAM.000631.php

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The Cap Dualism-Efficiency or Competition_ Crimson Publishers

 The Cap Dualism-Efficiency or Competition by Minko Georgiev* in Modern Concepts & Developments in Agronomy_ International Journal of Agronomy

 

Abstract
The Common Agricultural Policy of the EU (CAP) contains incentives for consolidation of resources and integration of organizations. The entire CAP follows the concept of efficiency achieved through product structure optimization and economies of scale. CAP imposes an advantage for the concept of efficiency at each level of the economic system. For this reason, integration-horizontal and vertical [1]-has been imposed as more important for farmers than competition. Such an approach stimulates large-scale exchange and consolidation of resources, at the same time being a prerequisite for problems for market competition. The Chicago School addresses the concept of efficiency in relation to the “antitrust paradox” [2]. Harvard authors propose that the “leverage effect” [3] can occur as a result of efficiency, meaning that the related markets could be influenced by some market players, and therefore discrimination against other subjects can emerge. Another way to achieve higher economies of scale is horizontal integration. Practically, however, in the course of resource exchange, certain actors can be excluded from the economic organization. The type of organizational structure determines the way of resource distribution and it is essential for competition. A critical analysis of the collision between competition and integration has been offered by Glick M [4]. Actually, efficiency may turn out to be in a conflict with competition

https://crimsonpublishers.com/mcda/fulltext/MCDA.000601.php

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The Use of Pulse Oximetry at High Altitude_ Crimson Publishers

 The Use of Pulse Oximetry at High Altitude by Markus Tannheimer* in Research & Investigations in Sports Medicine_ Journal of Sports Medicine

 

Abstract

More than 100 million people visit high mountain regions every year and engage there in sporting activities [1]. Due to the reduced air pressure at altitude, the arterial oxygen saturation (SaO2) decreases [2,3]. The resulting oxygen deficiency in the tissue is the cause of acute mountain sickness (AMS) in previously healthy individuals [4-6]. It can easily be quantified noninvasively by pulse oximetry [3,7,8]. For this reason, the pulse-oximetric determination of oxygen saturation (SpO2) during altitude stays is used frequently for the diagnosis of AMS as well as for the assessment of altitude acclimatization status [3,5,7,9-11]. However, pulse oximetry measurements at altitude are much more complex and error-prone than at sea level [8,10,12,13]. Therefore, the use of pulse oximetry at high altitude is viewed critically by experts [8-10,14]. This mini-review describes the special aspects of pulseoximetric measurements at altitude and gives recommendations on how to perform them.

There is a consensus to use pulse oximetry for monitoring ill persons at altitude [10,14,15]. Concerns exist about possible incorrect measurements due to cold-related deficient blood circulation or movement artifacts [10,16,17]. In our opinion, movement artifacts fundamentally contradict the defined measurement situation of a resting measurement. The test person sits quietly in warm clothing with warm fingers, the sensor is protected from sunlight, while an experienced examiner visually determines the representative mean value of the 2-3-minute measurement interval [5,10,12]. If for whatever reason, the measurement is disturbed due to movement, it is discarded and the measurement is repeated after standardization and optimizing the measurement situation

https://crimsonpublishers.com/rism/fulltext/RISM.000631.php

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Negative Health Effects of the International Space Station_ Crimson Publishers

 Negative Health Effects of the International Space Station by Margaret Maclagan* in Gerontology & Geriatrics Studies_ International Journal of Gerontology

 

Abstract

The dazzling weapon was tested against volunteers firing assault weapons, sniper rifles, and machine guns at targets protected by Filin from two kilometers away. All the participants experienced difficulties aiming, and 45% had complaints of dizziness, nausea, and disorientation. Twenty percent of volunteers experienced what Russian media has characterized as hallucinations. Participants described seeing floating balls of light. But there are concerns about cloud seeding’s long-term impacts. For example, it’s unclear how making it rain in one village affects a neighboring village, cities, etc. It’s also up for debate who “owns” the water-such as which state or company-that comes out of the clouds. There are also environmental questions, such as ones related to the long-term impacts of silver iodide. Although some critics may have concerns about companies impacting the weather with the International Space Station (ISS) that they are “playing God.” One of the main causes of a Climatic Changes in our recent World are artificial interventions into Global and different Local Weather from the International Space Station regulated by Russia

https://crimsonpublishers.com/ggs/fulltext/GGS.000601.php

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The Effect of Patellar Button Placement on Gait and Patellar Stresses Following Total Knee Arthroplasty_ Crimson Publishers

 The Effect of Patellar Button Placement on Gait and Patellar Stresses Following Total Knee Arthroplasty by Dmitriy Peresada* in Orthopedic Research Online Journal_ Orthopedic Research journal

 

Abstract

Background: In total knee arthroplasty with patellar resurfacing, surgeons are often faced with a choice of where to position the patellar button. Patellar button positioning has been studied in relation to patellar tracking and risk of subluxation. Consequently, medial placement has been recommended. However, postoperative gait and risk of periprosthetic complications have not been thoroughly addressed in relation to patellar button positioning.

Objective: To establish a generalized criterion for patellar button positioning during total knee replacement (TKA) to reduce the risk of postoperative gait abnormalities, patellar fracture, pain, and stress wear.

Methods: Five distinct button positions were analyzed. A previously-validated gait model was customized with data obtained from cadaveric patellae to evaluate individual quadriceps forces. The maximal combined quadriceps force during gait was applied to a finite element analysis model to calculate patellar von Mises stresses for all button positions, as well as for a large diameter button covering most of the patellar resurfaced area.

Results: Significant differences were found in average forces exercised by individual quadriceps muscles during gait. Distal and medial configurations produced the lowest individual quadriceps muscle forces. Bone stress ranged from 12.45MPa to 12.57MPa. The button stress ranged from 11.27MPa to 17.20 MPa, with distal and centered placement, respectively

https://crimsonpublishers.com/oproj/fulltext/OPROJ.000631.php

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Importance of the Olphactory Environment in the Laboratory Animal Science_ Crimson Publishers

Importance of the Olphactory Environment in the Laboratory Animal Science by Fekete S* in Approaches in Poultry, Dairy & Veterinary Sciences_ Dairy and Veterinary Sciences journal

 

Abstract

The 3rd R, the refinement is receiving more and more attention. The optimazing of the auditory and olphactory environment of the laboratory animals is essential, because the environmental smells influence the behaviour and occasionally the epigenetics of mammals. According to the characteristics of the smell substances a chemical map is developed in the olphactory bulb. The vomeronasale organ (VNO) has an important role in the pheromonetransfered communication [1]. The VNO is expressing specific major histocompatibility genes, too. In horses and felidae a specific behaviour form, the Flehmen-reaction facilitates pheromone molecules to get the VNO. The intraspecific communication is attained by means of the pheromones, especially in the social and sexual relations. The kairomones are functioning in the communication between species. The interomones are smell compounds influencing the behaviour or physiology of other species, with or without a positive or negative effect for the releaser. Some interomes may decrese the stress of other species [2], having a significance of animal welfare.

https://crimsonpublishers.com/apdv/fulltext/APDV.000631.php

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