“Triple-Tube-Ostomy” Technique for Management of Duodenal Injuries: A Systematic Review and Meta-Analysis_Crimson Publishers

“Triple-Tube-Ostomy” Technique for Management of Duodenal Injuries: A Systematic Review and Meta-Analysis by Hisham Bahmad in Research in Pediatrics & Neonatology: Babies

Abstract:

Background: Isolated duodenal injury following blunt or penetrating trauma remains an extremely rare and one of the most challenging hitches confronting trauma surgeons. Triple-tube-ostomy (TTO) technique involving gastrostomy, reverse duodenostomy, and feeding jejunostomy tubes insertion has shown promising results during conservative management of duodenal injuries.

Objective: We aim through this paper to report a successfully managed case of isolated incomplete transverse duodenal injury managed by TTO technique in a 14-year-old boy who presented with severe abdominal pain, one day after sustaining ablunt abdominal trauma due to fall from height. In addition, we aimed to systematically review the literature for the usage and outcomes of the TTO surgical procedure, and evaluate its efficiency and effectiveness in the management of duodenal injuries.

Data Sources: OVID/Medline, PubMed, and Scopus databases were lastly searched on December 8th, 2016 to identify all published research studies on duodenal injuries treated by this surgical technique.

Study Selection: Studies reporting cases of duodenal injuries that were managed by TTO were warranting inclusion.

Data Extraction and Synthesis: Both CARE and PRISMA guidelines were followed for conduction and reporting of this study. Throughout the whole review process, two reviewers worked independently and in duplicate to screen titles, assess full texts for eligibility, and abstract data.

Results: Six articles were included in this review. Sixty five cases were reported to have undergone TTO in world literature. Majority of the cases were performed after surgical repair of giant duodenal ulcers, only 2 cases were reported due to perforations following trauma. While majority of cases had uneventful recovery, complications such as wound infections and dehiscence were reported. Mean length of hospital stay was found to be 20.5 days. Mortality occurred in 3 cases.

Conclusion and Relevance: The positive outcomes of our reported case and the structured evaluation of the published studies suggest effectiveness of usage of “triple-tube-ostomy” surgical procedure for management of duodenal injuries. However, further studies are needed to assess the usage of this technique in management of duodenal injuries in comparison to other classical surgical techniques.

https://crimsonpublishers.com/rpn/fulltext/RPN.000534.php

For more open access journals in Crimson Publishers

please click on https://crimsonpublishers.com/

For more articles in open access journal of  Babies 

please click on https://crimsonpublishers.com/rpn/

Follow On Publons  : https://publons.com/publisher/6342/crimson-publishers
Follow On Linkedin : https://www.linkedin.com/company/crimsonpublishers

PEX12 Novel Mutation: A Case Report on Iranian Girl with Childhood Onset Peroxisomal Disorder: Pseudo ALD?: Crimson Publishers

PEX12 Novel Mutation: A Case Report on Iranian Girl with Childhood Onset Peroxisomal Disorder: Pseudo ALD? by Tabarestani S in Research in Pediatrics & Neonatology: Peroxisomal Disorder

Objective: To report a 7 years old girl with genetic and biochemical characteristics of zellweger spectrum disorder who presented with phenotype and neuro imaging findings of adrenoleukodystrophy.

Methods: Target gene sequencing was performed by using a custom designed panel for this patient with focused mutation analysis on 16 peroxisomal genes included in the panel. Sanger sequencing was used to confirm the identified mutation.

Results: This patient was homozygote for a missense mutation in exon 2 of the PEX 12 gene; c.541T>G (p.Tyr181Asp) which is a conserved residue in the N-terminal region crucial for localization to peroxisomes. Her parents and healthy sister were also found to have the same heterozygote mutation.

Conclusion: We suggest that PEX 12 gene mutations with a milder phenotype may be a potential candidate for posterior dominant leukodystrophy of childhood resembling X-linked ALD. This is entitled to pseudo- ALD and may be a diagnostic possibility in patients who develop ALD phenotype and neuroimaging particularly, in girls.

https://crimsonpublishers.com/rpn/fulltext/RPN.000524.php

For more open access journals in Crimson Publishers please click
on https://crimsonpublishers.com/

For more articles in open access journal of  Peroxisomal Disorder please click

on https://crimsonpublishers.com/rpn/

Obstructed Diaphragmatic Hernia in Children: Report of Two Cases: Crimson Publishers

Obstructed Diaphragmatic Hernia in Children: Report of Two Cases by Samiul Hasan in Research in Pediatrics & Neonatology:  Children 

Congenital diaphragmatic hernia usually present in early neonatal period. Few cases present later in child hood with respiratory symptoms but presenting with intestinal obstruction is very rare. We describe two patients of congenital diaphragmatic hernia presenting with intestinal obstruction.

https://crimsonpublishers.com/rpn/fulltext/RPN.000519.php

For more open access journals in Crimson Publishers

 please click on https://crimsonpublishers.com/

For more articles in open access journal of  Children  

 please click on https://crimsonpublishers.com/rpn/