Crimson Publishers High Impact Journals

Showing posts with label journal of cardiology & heart diseases. Show all posts
Showing posts with label journal of cardiology & heart diseases. Show all posts

Monday, July 19, 2021

A Shift in Paradigm of Disease Profile in Kenya: Should we be Cautious?_ Crimson Publishers

 A Shift in Paradigm of Disease Profile in Kenya: Should we be Cautious? by Romani I* in Open Journal of Cardiology & Heart Diseases_ journal of cardiology & heart diseases

 

Abstract

As per the World Health ranking in 2014 Kenya stands 149th in the world in census of coronary artery diseases. 2.74% of the total death. The main cause of death in communicable disease are influenza, HIV/AIDS, diarrhea, malnutrition etc. The age adjusted death rate being 53.61/100,000 population. Kenya is experiencing epidemiological transition in disease burden from infection to non-communicable condition (NCD), which are a major health concern with significant social and economic implication. The increasing coronary artery disease (CAD) may be due to adoption of unhealthy lifestyle (lack of exercise, increase in take of fast food) etc. The major risk factors are: diabetes mellitus, hypertension, smoking, excessive alcohol intake, stress etc.

Cardiovascular disease amount to most of the NCD deaths around the world (17.5 Million annually). NCD in Kenya amount to 27% of the total death, more than 50% of total hospital admission in Kenya. The major NCD being cardiovascular conditions, cancer, diabetes, chronic obstructive pulmonary disease (COPD) and their sequel. A comprehensive study was therefore needed to examine the prevalence and the magnitude of common risk factors for NCDs in Kenya which is useful to the Ministry of Health, different government sectors and county governments to establish interventions that are based on local risk factor burden. Mortality due to CAD in Kenya is between 6.1%-8% while autopsy study suggest it is more than 13%. The risk factors has increased over the last 20 years. Rheumatic Heart disease constitutes a major cause of cardiovascular diseases both in children and adults in Kenya. The annual mortality rate decreased from 19.8% since 1990.

 https://crimsonpublishers.com/ojchd/fulltext/OJCHD.000551.php

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Thursday, April 22, 2021

A Case Report of Coarctation of Aorta Presenting as ST Elevation in Anterior Chest Leads of ECG with Severe Left Sided Neck Pain_ Crimson Publishers

 A Case Report of Coarctation of Aorta Presenting as ST Elevation in Anterior Chest Leads of ECG with Severe Left Sided Neck Pain by Hammad S* in Open Journal of Cardiology & Heart Diseases_ journal of cardiology & heart diseases

 

Abstract
Coarctation of aorta is characterized by narrowing of the aortic lumen. Complex lesion are complicated by associated cardiac anomalies and picked in infancy while simple coarctations are not diagnosed until adulthood when it manifests as secondary hypertension or its complications. We are reporting a case of severe coarctation of aorta which presented as ST elevation on anterior chest leads with severe sudden onset left sided neck pain mimicking anterior wall myocardial infarction and patient was thrombolysed due to dynamic ECG changes and new onset severe left sided neck pain. Clinicians and cardiologists worldwide should be aware of such occurrence to prevent unnecessary thrombolysis in patients not fullfiling other criteria of myocardial infarction. Bedside echo assessment and highly sensitive cardiac troponin and inflammatory markers (hs-CRP) could help in correctly aiding to diagnosis and preventing such occurrences from happening which can complicate into life threating hemorrhage

https://crimsonpublishers.com/ojchd/fulltext/OJCHD.000550.php

Crimson Publishers: https://crimsonpublishers.com/

For more articles in journal of cardiology & heart diseases,
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Sunday, February 7, 2021

Vagally Mediated Bradycardia and Increased Vagal Tone: Interest of Cardiovascular Autonomic Reflexes Testing_ Crimson Publishers

 Vagally Mediated Bradycardia and Increased Vagal Tone: Interest of Cardiovascular Autonomic Reflexes Testing by Romani I* in Open Journal of Cardiology & Heart Diseases_ journal of cardiology & heart diseases

 

Abstract

Introduction: The autonomic nervous system (ANS) controls all body functions. Dysregulation of this system may be responsible of bradycardia. The main objective of our study is to describe the autonomic profile of patients with bradycardia and to determine, through testing cardiovascular autonomic reflexes its involvement in the pathogenesis of idiopathic symptomatic bradycardia.

Material and methods: This are a retrospective study including 72 patients with bradycardia. The study was conducted in the ANS unit of the cardiology department in Mohamed VI hospital of Marrakech. All patients had clinical examination, electrocardiogram, biological exam and autonomic nervous system tests.

Results: The average age of the patients was 44 years old with a female predominance. The mean heart rate was 50bpm. Patients had polymorphic functional symptoms. The autonomic profile of patients with bradycardia revealed a significant predominance of vagal hyperactivity, which is present in 83.3% of patients. Increased vagal tone was associated with a peripheral sympathetic alpha deficiency in 30,5% of the cases, a peripheral sympathetic beta deficiency in 25% and even a peripheral sympathetic beta hyperactivity in 54,1% of patients. The main autonomic syndromes found were: postural orthostatic tachycardia syndrome (POTS) in 34,7% of patients, orthostatic hypotension in 25% of the cases, vasovagal syncope in 8,3%, and the baro-receptor abnormality in 12,5% of the patients. The treatment, depending on the autonomic abnormality showed an improvement in the functional state of the patients.

Conclusion: Autonomic profile study helps to explain the causes of symptoms described by the patients with bradycardia whose clinical and conventional paraclinical examinations are normal.

https://crimsonpublishers.com/ojchd/fulltext/OJCHD.000549.php

Crimson Publishers: https://crimsonpublishers.com/

For more articles in journal of cardiology & heart diseases,
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Thursday, November 5, 2020

Evaluation of Cardiac Biomarkers after Treatment with the Biofield Treated Test Item in Cardiomyocytes Cell Line (H9c2)_ Crimson Publishers

 Evaluation of Cardiac Biomarkers after Treatment with the Biofield Treated Test Item in Cardiomyocytes Cell Line (H9c2) by Snehasis Jana* in Open Journal of Cardiology & Heart Diseases_ journal of cardiology & heart diseases

 

Abstract

The study objective was to evaluate the cardioprotective activity of Biofield Energized test item (DMEM) in rat cardiomyocytes (H9c2) cells. The test item (DMEM medium) was divided into three parts, first part received one-time Consciousness Energy Healing Treatment by a renowned Biofield Energy Healer, Dahryn Trivedi and was labeled as the one-time Biofield Energy Treated (BT-I) DMEM, while second part received the two-times Biofield Energy Treatment and is denoted as BT-II DMEM. The third part did not receive any treatment and defined as the untreated DMEM group. MTT cell viability assay of the test sample showed more than 95% viable cells in the BT-I and BT-II groups, respectively suggested a nontoxic nature of the test substance. The BT-II group showed 16.28% restoration of cytoprotective function compared to the t-BHP induced group. The level of lactate dehydrogenase (LDH) was significantly inhibited by 48.36% and 47.89% in the BT-I and BT-II groups, respectively compared to t-BHP induced group. Level of creatine kinasemyocardial band (CK-MB) was significantly suppressed by 59.5% in the BT-I and BT-II groups compared to the t-BHP induced group. Reactive oxygen species (ROS) level was significantly suppressed by 120.08% and 116.20% in the BT-I and BT-II groups, respectively. Besides, BT-I and BT-II groups showed 33% and 48.5% inhibition of apoptotic cells, respectively compared to the t-BHP induced group. Altogether, result suggested that Biofield Treated test items significantly improved different cardiac parameters. Thus, Consciousness Energy Healing (The Trivedi Effect®) Treatment could be utilized as a cardio-protectant against several cardiac disorders such as heart failure, coronary artery disease, heart attack, congenital heart disease, cardiomyopathy, arrhythmias, etc

https://crimsonpublishers.com/ojchd/fulltext/OJCHD.000548.php

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Friday, July 17, 2020

Essential Hypertension in the Elderly: To Treat or Not to Treat? A Therapeutic Dilemma for the Geriatric Cardiologist_ Crimson Publishers


Essential Hypertension in the Elderly: To Treat or Not to Treat? A Therapeutic Dilemma for the Geriatric Cardiologist by Akhtar Khan* in Open Journal of Cardiology & Heart Diseases_ journal of cardiology & heart diseases

 

Abstract
Essential hypertension, the most common type, is an important cause of morbidity and mortality in the elderly, a rapidly growing section of the population. It is a sad reality that until the 1950s treating benign hypertension was not thought to be necessary. The tragic death of Franklin Delano Roosevelt on April 12, 1945 at the age of 63 years, with a blood pressure of 350/195mmHg, and without treatment shocked the healthcare community. Now, with extensive research, the availability of affordable and effective treatments and lifestyle measures, freedom from unfounded phobias of adverse drug effects, and new approaches such as aroma, colour and music therapy have improved the quality of life for hypertensives generally and especially the elderly.

Introduction
“There are few stories in the history of medicine that are filled with more errors or misconceptions than the story of hypertension and its treatment.“_ Prof Marvin Moser (1925-2015)-Yale University School of Medicine.

Hypertension (HTN) is defined as: Having a systolic blood pressure (SBP) of 140mmHg or greater OR having a diastolic blood pressure (DBP) of 90mmHg or greater OR taking antihypertensive medication OR having been told at least twice by a physician or other health professional that one has HTN [1]. Prof. John Hay (University of Liverpool), while delivering a lecture in Bradford on February 25th, 1931, under the auspices of the British Medical Association, remarked “It is agreed that a high arterial pressure is essential for the efficient performance of muscular work”. He added “There is some truth in the saying that the greatest danger to a man with high blood pressure lies in its discovery, because then some fool is certain to try and reduce it [2]. However, research has since established that HTN (“The Silent Killer”) is a persistent non-physiologic elevation in blood pressure necessitating timely pharmacological and non-pharmacological interventions. Essential hypertension (‘Essentielle hypertonie’) is the most common type of HTN accounting for 95% of hypertensives.


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