Efficacy of Silk Fibroin Based Bio-Ink in 3D Printing for Tissue Engineering by Utibe Udonwa* in Trends in Textile Engineering & Fashion Technology_ Textile Science Engineering Journal
Abstract
Today,
countless peoples are suffering and dying from various diseases and one of the
reason being the non-compatibility and failure of life saving drugs. In fact 90
percent of the new drug that are tested in labs, on animals trials which are
promised to cure the problems actually fail in certain humans. Sometimes, the
drug failures during human trials are tragic enough to result in rapid multiple
organ failures making the
human tester incapable from leading his/her normal lifestyle [1]. The drug that
demonstrated its ability to cure in the laboratories may not work same on all
people as each human body is unique. This poses to be a major challenge for the
drug manufacturers whose significant point of concern would be to develop safe
and effective drug which is a risky, time consuming and highly expensive
process in reality. In finding solutions to avoid such devastating drug
failures and detrimental side effects on human trials, engineering and
biotechnologists have come forward to work on developing human tissues outside
the body and test the drugs on these tissues. As each individual are different
from one another, the tissues developed form the body cells would be unique and
testing the drugs on such
tissues would accurately determine its safety, compatibility and effectiveness
prior to human trials [2]. This can ease the process of drug development by
reducing our reliance in animal trials and further increasing the acceptance
rates with almost zero chance of rejection, ultimately ending up with better,
safer and cheaper drugs.
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