Bio-Resources Market Chain Linkages and an Opinion for its Sustainable Utilization in India- Crimson Publishers

Bio-Resources Market Chain Linkages and an Opinion for its Sustainable Utilization in India by Suresh Jagtap in Advances in Complementary & Alternative Medicine: Crimson Publishers- Alternative and Complementary Medicine Journal

Throughout the world, there is large demand of the bioresources and many people are still dependant on it. Medicinal plants are one of the parts of these bio-resources. More than 7,000 species from India are considered as medicinal plants. However, all these species do not have high market demands. Many of them are used by local people and tribal by traditional ways. Few people are well practicing commercial use of medicinal plants for various purposes. As per the reports of Planning Commission in 2000, it has been estimates that, there are over 7,800 manufacturing units in India related to the bio-resources, indicating consistently increasing demand since last decade.

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Complex Neurological Decision_Crimson Publishers

Complex Neurological Decision by Ghassan Haddad in Techniques in Neurosurgery & Neurology: Crimson Publishers_Clinical Neurology and Neurosurgery

Neurologists are faced with one great challenge when facing patients with atrial fibrillation who developed an acute ischemic stroke. One question arises.

When to initiate or resume anticoagulation to prevent a recurrent stroke or embolization?

Review of the literature reveals 2 views

1. The first view was a Cochrane reviews done in 2008 that showed that early anticoagulation within two weeks of stroke onset was associated with fewer recurrent strokes compared to no anticoagulation but at the costs of increased symptomaticintracranial hemorrhages. The conclusion was that early anticoagulation did not improve outcomes [1].

Another studies done by Italians scientist showed that early anticoagulations within 48 hours of stroke had no benefit compared to aspirin or placebo [2].

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Could Fast Response Curtail New Congo Ebola Virus Outbreak?_Crimson Publishers

Could Fast Response Curtail New Congo Ebola Virus Outbreak? by Philips Akinwole in Cohesive Journal of Microbiology & Infectious Disease: Crimson Publishers:  open infectious diseases journal impact factor

The 2013-2016 West Africa Ebola virus outbreaks was the first anywhere in the world to reach epidemic proportions - causing approximately 28,616 suspected cases and 11,310 reported deaths. The first cases of the deadly diseases were reported in Guinea in December 2013 and later spread to neighboring Liberia and Sierra Leone, with minor outbreaks in Nigeria and Mail and cases also being exported to Europe and the USA. WHO was widely criticized for its delay in taking actions to address the epidemic. Expected early alert is meant to mobilize foreign aids and actions. On August 8, 2014, WHO officially declared the outbreak a publichealth emergency of international concern. This declaration triggered a surge in outside help, for instance, U.S. President Barack Obama ordered up to 3,000 troops to Liberia and promised medical resources and the constructions of as many as 17 Ebola treatment centers in the region, with about 1,700 treatment beds. Britain pledged £20 million to build Ebola clinics, China sent a 59-person lab team and Cuba sent more than 400 health workers (Figure 1).

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Archaea in Food Microbiology: Are They Really Possible Threat or Not?_Crimson Publishers

Archaea in Food Microbiology: Are They ReallyPossible Threat or Not? by Mostafa Essam Ahmed Mostafa Eissa* in Novel Techniques in Nutrition and Food Science: Crimson Publishers_Neonatology Open Access Journals

In the world of continually growing populations of health compromised individuals, there is an expanding list of pathogenic microorganisms. The list normally includes mainly bacteria, fungi, viruses and protozoa. While the discovery of domain Archaea is considered relatively recent, its biological interaction with human life is still mysterious at different perspectives. This domain is highly distributed globally, even in the harsh environmental conditions, where the possibility of life form existence was excluded. The difficulty of culturing many of Archaeal organisms using conventional culture media is a true barrier for any detection and/or studying of these entities. Only when new bimolecular technologies came into play, some of the ambiguity of these single-celled organisms has begun to resolve. Accordingly, many of Archaeal species may pass the quality control tests undetected to the final consumers. No solidly established data are available till now on our hand about spoilage of food products either preserved or not on storage by Archaea. Moreover, all studies about probable link between certain disease conditions and the presence of Archean are speculating and no true relation was established till now. Thus, the disregard of these microorganisms-especially those on, inside, very close to the human body and the surrounding environment-as potential threat to our life may be a haste discussion when no scientifically rational evidence are available till now. Extensive studies are required to solve this dilemma in a timely manner.

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Perforated Appendicitis Preoperatively complicated by Multiple Intra-Abdominal Abscesses | Crimson Publishers

Perforated Appendicitis Preoperatively complicated by Multiple Intra-Abdominal Abscesses by Tarik Zahouani in Surgical Medicine Open Access Journal

Acute appendicitis is the most common surgical emergency in the pediatric population [1]. Complications are seen in 30 to 40% of cases, and include perforated, gangrenous, intra-abdominal abscess and peritonitis [1]. The rate of perforated appendicitis is higher in children compared to adults and varies from 30% to 74% [2]. We report a case of perforated appendicitis preoperatively complicated by multiple intra-abdominal abscesses.

https://crimsonpublishers.com/smoaj/fulltext/SMOAJ.000528.php

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Appraisement of Genetic Variability and Character Association of Bitter Gourd (Momordica charantia L.) Land Races for Yield and Yield Contributing Characters in Bangladesh | Crimson Publishers

Appraisement of Genetic Variability and Character Association of Bitter Gourd (Momordica charantia L.) Land Races for Yield and Yield Contributing Characters in Bangladesh by Hasan Khan M in Journal of Biotechnology and Bioresearch

 A field experiment was conducted with 20 genotypes of bitter gourd (Momordica charantia L.) at the experimental field of Sher-e-Bangla Agricultural University, Dhaka, to study the variability among the genotypes for yield and yield contributing characters, estimate genetic parameters, association among the characters and their contribution to yield during April 2015 to September 2015. There was a great deal of significant variation for all the characters among the genotypes. Considering genetic parameters high genotypic co-efficient of variation (GCV) was observed for fruit weight, yield per plant and fruit length whereas low genotypic co-efficient of variation (GCV) was observed for nodes per vine, days to first male and female flowering. In all the cases, it was found that phenotypic co-efficient of variation was greater than genotypic co-efficient of variation which indicated a wide variability among the genotypes and offered better scope of selection. The accession G9 and G13 were the lowest vine length of 3.90m while G8 was the maximum vine length for 4.83. The minimum and maximum branches per vine were required by the genotypes G3 and G4, respectively. The maximum nodes per vine (87.33) were recorded by the genotype G9 and the lowest nodes per vine (78.00) were recorded by G19. The earliest male flowering was recorded in G17 and G2 genotype showed the late flowering. The maximum fruit length was recorded in the genotype G7 and minimum fruit length in the genotype G1.

The maximum fruit diameter was recorded in the genotype G1 and the minimum fruit diameter in the genotype G4. The minimum fruit weight was recorded by the accession G4 and accession G16 showed the maximum fruit weight. The line G2 showed the minimum fruits per plant and the maximum fruits per plant were recorded in the accession G9. The highest fruit yield per plant was recorded by the accession G19 while accession G14 showed the lowest fruit yield per plant. High heritability (>60%) was observed for the characters like vine length, branches per vine, nodes per vine, fruit length, fruit weight, fruits per plant and fruit yield per plant. The high heritability coupled with high genetic advance in percent of mean observed in branches per vine, fruit length, fruit weight and fruit yield per plant suggested that effective selection may be done for these characters. Fruit yield per plant showed the highest positive direct effect (0.88) with branches per plant. Firstly, genotypes G19, G9, G12 and G4 could be included in the furthest study in view of fruit yield for releasing as bitter gourd verities. Secondly the maximum variability found for branches per vine, fruit length, fruit weight and fruit yield per plant. So, selection based on these characters could be effective for the improvement of bitter gourd yield.

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Mentored by Me-Crimson Publishers

Mentored by Me by  Rakesh Bhargava in Crimson Publishers: Annals of Medicine and Surgery

Crimson Publishers: Annals of Medicine and Surgery

Surgery I was given to understand was an art learnt by apprenticeship. When I was choosing a subject for my postgraduation, therefore, the paramount consideration was the mentor. I chose Dr P K Sethi, with whom the Jaipur Foot is associated.

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Dexmedetomidine as a Sole Sedative Agent versus Propofol for Sedation during Upper and Lower Gastrointestinal Endoscopies | Crimson Publishers

Dexmedetomidine as a Sole Sedative Agent versus Propofol for Sedation during Upper and Lower Gastrointestinal Endoscopies by Alaa Ali Elzohry in Developments in Anaesthetics & Pain Management

Introduction and objectives: Diagnostic and therapeutic procedures recently are done in gastroenterology setup as a part of fast-track concept. A major volume of gastrointestinal procedures are performed routinely on daycare basis under sedation as upper and lower GIT endoscopy. Many anesthetic agents used to provide sedation for these procures. Propofol, opioids, and midazolam form the backbone of the various regimes employed in the endoscopic suites all over the world. Dexmedetomidine is a pharmacologically active selective α 2-adrenergic receptor agonist. It was approved it in the intensive care unit (ICU) for sedation and analgesia for the duration of less than 24 hours. The aim of this study was to study efficacy and safety of Dexmedetomidine efficacy as sole sedating agent versus propofol for sedation during upper and lower GIT endoscopy.

Methods: This randomized controlled trial was carried out on 60 patients of either sex, aged 21-70 years of age undergoing upper and lower GIT endoscopy, with ASA I-II. Patients were randomly assigned into two groups, (30 patients in each group).

Dex group: Sedation was induced by loading dose of (dexmedetomidine 1μg/kg) followed by infusion of (dexmedetomidine 0.8μg/kg /h) Propofol group: Sedation was initially started by bolus dose of 0.5mg/kg propofol IV Then, infusion was started at the rate of 50μg /kg/min. Upper and lower GIT endoscopies were carried out in the usual standard manner for all patients, then patients were discharged to PACU after attaining an Aldrete Recovery Scale Score of 9-10 Time taken to achieve this score was recorded. The patient’s vital signs, Respiratory complications, VAS score for pain measurement, PONV, and any other adverse events were recorded.

Results: There was significant decrease in (HR and MAP) but not respiration rate (RR) and SpO2, in (Dex group) during the procedure and early post-operative (P. value 0.000**). But during the remaining of post-operative periods (HR and MAP) were comparable. VAS pain scores in both groups were decreased in comparable manner at all measured time points. But complications (atthythmia, air way obstruction, nausea, and vomiting) was significantly increased in Propofol group (P. value 0.001**). Mean time to achieve RSS 3-4 was 6 (±1.5) min in Dex group versus 9 (±1.9) min in Propofol group (P< 0.005) and to achieve an Aldrete Recovery Scale Score of 9-10 was 8 (±2.1) min in Dex group versus 6 10 (±1.6) min in Propofol group (P< 0.029).

Conclusion: In conclusion, there is evidence to support dexmedetomidine as a potential sole sedative agent in small diagnostic and therapeutic procedures like GIT endoscopies, our study support these evidences and although dexmedetomidine resulted in longer onset and recovery, more side effects but sufficient levels of sedation and analgesia are good advantages to use it as sole sedating agent.

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