Complex Neurological Decision by Ghassan Haddad in Techniques in Neurosurgery & Neurology: Crimson Publishers_Clinical Neurology and Neurosurgery
Neurologists are faced with one great challenge when facing patients with atrial fibrillation who developed an acute ischemic stroke. One question arises.
When to initiate or resume anticoagulation to prevent a recurrent stroke or embolization?
Review of the literature reveals 2 views
1. The first view was a Cochrane reviews done in 2008 that showed that early anticoagulation within two weeks of stroke onset was associated with fewer recurrent strokes compared to no anticoagulation but at the costs of increased symptomaticintracranial hemorrhages. The conclusion was that early anticoagulation did not improve outcomes [1].
Another studies done by Italians scientist showed that early anticoagulations within 48 hours of stroke had no benefit compared to aspirin or placebo [2].
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