The Impact of Adjuvant Chemotherapy on Health-Related Quality of Life (HR-QoL), A Prospective Multicenter Measurement Study by Antoine Abi Abboud* in Gastroenterology Medicine & Research_ Gastroenterology Open Access Journals
Introduction
Chemotherapy is one of the
most commonly employed cancer treatments since its use provides a strong
evidence for disease-free survival as well as overall survival for several
cancer types. This type of treatment is associated with detrimental side
effects that are difficult to tolerate and that impact the quality of life
(QOL) of patients on different levels. As more patients undergo adjuvant
chemotherapy, there has been a growing interest in investigating its impact on
health-related quality of life (HRQOL). To our knowledge, most published literature
focuses on HRQOL at specific time points during chemotherapy and only limited
data describes the dynamics of HRQOL starting before treatment, during the
complete duration and after completion of chemotherapy.
Objective: The objective of
this study is to evaluate the impact of adjuvant chemotherapy on a patient’s
quality of life before the start, half-way through, at the end and 3 months
after the end of chemotherapy and to examine whether individual differences in
quality of life among adjuvant chemotherapy patients could be accounted for by
selected demographic and
medical characteristics
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