The Relationship Between Type 2 Diabetes Mellitus and Osteoporosis in Elderly Patients: A Retrospective Study_ Crimson Publishers

 The Relationship Between Type 2 Diabetes Mellitus and Osteoporosis in Elderly Patients: A Retrospective Study Anood Jamal Alshaali* in Advancements in Case Studies_ Advancements in Case Studies

Abstract

Type 2 diabetes mellitus (T2DM) effect bone metabolism, but the relationship of T2DM with bone mineral density remains inconsistent across studies. The objective of this study was to determine the relationship between osteoporosis and T2DM in elderly patients.A total of 313 elderly was included in the study with a mean age of 68.20±7.07 years. The prevalence of osteoporosis in this study was 39.5%. The results showed that, non- diabetic elderly had higher prevalence of osteoporosis in comparison to diabetic elderly (44.0% and 33.1%, respectively). This difference was statistically significant (P=0.007). It was observed that males had higher femur and lumbar spine BMD in comparison with females. The present study gave better understanding of the effect of diabetes mellitus on bone architecture will help to improve the quality of provided health services at the primary health care level hence, improving the outcomes.

Introduction

Osteoporosis is defined as a metabolic skeletal disorder characterized by compromised bone strength and altered bone quality along with micro-architectural abnormalities predisposing a person to an increased risk of fracture, hence leading to a significant morbidity and mortality [1,2]. The risk of osteoporosis increases with advanced age and is higher in women than in men. The lifetime risk of developing osteoporosis and osteoporotic fracture is estimated to be 30-50% in women and 15-30% in men [3]. The United Nation described population aging as a key demographic feature of the 20th century and stated that it will remain an important population issue throughout the 21st century. Elderly population forms a significant proportion of the world total population. In 2015, 12% of the 7.3billions living individuals were aged 60 years and above. This is expected to increase to 21.6% by 2050

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