Pre-Operative
IV Iron Infusion for Vascular Patients: Need for More Evidence by Ahmed Nassar and Bryce Renwick* in Surgical Medicine Open Access Journal_ Surgical
Medicine Open Access Journal
Introduction
Pre-operative anaemia is
present in approximately 30% of patients undergoing noncardiac surgery [1]. The
presence of pre-operative anaemia is the strongest predictor of perioperative
blood transfusion and is an independent risk factor for post-operative morbidity
and mortality [2]. It is well known that Red Blood Cells (RBC) transfusion can
increase the surgical length of stay, increase mortality in surgical patients,
and expose patients to the risk of circulatory overload, acute lung injury, and
immunosuppression [3-5]. Sufficient data exist to support intravenous iron as
efficacious and safe. Intravenous iron should be used as front-line therapy in
patients who do not respond to oral iron or are not able to tolerate it, or if surgery is planned for <6
weeks after the diagnosis of iron deficiency [6]. The European Medicines Agency
concluded that the benefits of i.v. iron exceed the risks when used appropriately
(correct indication and dose), without any difference in safety profile among available
formulations [7]. We report two vascular cases had peri-operative i.v iron
treatment for anaemia.
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