Comparison of Geriatric Assessment Tools in Patients with
Solid Malignancies by Antoine Abi Abboud* in Gastroenterology Medicine & Research_ Gastroenterology
Open Access Journals
Abstract
Background: Eastern Cooperative
Oncology Group Performance Status (ECOG
PS), and Karnofsky Performance Status (KPS) are well known screening tools
for older cancer patients. However, the Comprehensive Geriatric Assessment
score (CGA), which is a multidimensional evaluation of the older patient, is
less used in practice. Few comparative studies were done before and there is no
screening tool uniformly used worldwide.
Methods: One hundred patients
aged 65 years and older diagnosed with solid tumors were interviewed before starting
their first chemotherapy cycle.
The scores of ECOG PS, KPS and CGA were filled. The statistical analysis was
done using the Chi-square test.
Results: No correlation was found
between CGA fragile on one side and ECOG ≥2/ KPS ≤70% on the other side with a
p-value of 0.9 and 0.48 respectively. Forty three per cent of patients had a
good performance status according to ECOG PS and KPS despite a fragile CGA.
Conclusion: KPS and ECOG PS may not
be reliable for treatment decision making in the older oncology patient.
Keywords: Cancer; ECOG PS; KPS;
CGA; Chemotherapy
Abbreviations: CGA: Comprehensive
Geriatric Assessment; ECOG PS: Eastern Cooperative Oncology Group Performance
Status; KPS: Karnofsky Performance Status
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