Current Targets of Immune Suppression in Tumor Microenvironment_ Crimson Publishers

                                                           

Current Targets of Immune Suppression in Tumor Microenvironment by Shih-Hsien Hsu in Novel Approaches in Cancer Study

In the past years, scientists have discovered tumormicroenvironment (TME) as a comfort zone of cancer cells. Efforts are being globally made to disrupt this comfort zone of cancer cells. However, a despiteseveral effort, the complete blockage of tumor progression has not been achieved because of unclear cellular and molecular mechanisms of TME crosstalk. Cancer immunotherapy is one of the promising therapies that have the ability to disrupt TME by restoring the immune attack on malignant cells [1]. However, positive outcomes of immunotherapy have been reported only in few patients, suggesting a need for the unmasking of regulatory mechanisms.

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