Seroprevalence of anti-Toxoplasma gondii Antibodies Among Aborted Ladies Attended to Atbara Teaching Hospital, River Nile State by Ali Elamin Nasir Hamad* in Advancements in Bioequivalence & Bioavailability_ Bioequivalence And Bioavailability International Journal
Abstract
This
cross-sectional study was conducted in Atbara area-River Nile state throughout
February to November 2017. The purpose of this study was to determine the
sero-prevalence of Toxoplasmosis among aborted women. One hundred and fifty-two
subjects with the age ranged between 25-49 years old of mean age was 38+10 were
included. Blood samples were taken from all subjects. All samples were examined
to detect Toxoplasma gondii antibodies by using Latex, ICT and ELISA techniques. The study
showed that the overall sero-prevalence of Toxoplasma parasite by different
techniques was as follows: 35.5% by ELISA technique, 33.6% by Latex
agglutination technique and 22.4% by ICT technique.
The overall prevalence of antibodies increased gradually with age reaching 54.6% in the age group (41-49) year followed by 32.9% in age group (31-40) year, then 12.5% in age group (20-30) year. Assuming ELISA technique as the gold standard method, the sensitivity and specificity of the LATEX technique were 94% and 100%, and for ICT technique were 64% and 100% respectively. The study found that Toxoplasma antibodies are more prevalent in women in contact with cats than in women who do not contact with cats.
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