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Wednesday, September 9, 2020

Strategies to Reduce Cerebral Palsy in Perinatal Medicine_ Crimson Publishers

 Strategies to Reduce Cerebral Palsy in Perinatal Medicine by  Kazuo Maeda* in Degenerative Intellectual & Developmental Disabilities_ Journal of Intellectual and Developmental Disability

 

Abstract

Aims: To prevent fetal brain damage and cerebral palsy (CP).

Methods: FHR score was studied with objective FHR changes. The FHR and fetal movements were recorded in actocardiogram (ACG). Computerized diagnosis, hypoxia index and GLHW, clinical ultrasound tissue characterization, were used for the diagnosis.

Result: FHR increased when fetus moved, and hypoxic damage was shown by the loss of acceleration followed by the loss of variability. Physiologic sinusoidal was diagnosed by actocardiogram. Caesarean delivery at the loss of acceleration and reduced variability will reduce cerebral palsy. Sum of duration of repeated FHR decelerations was main component of hypoxia index (HI). The cerebral palsy (CP) will be prevented by the early delivery performed if the HI is less than 25. Fetal growth restriction and asphyxia were treated by maternal heparin therapy in the case of placental intervillous space fibrin deposit, detected by high placental GLHW. Fetal brain periventricular echodensity (PVE), diagnosed by GLHW, followed by neonatal PVL and CP, disappears in the full term delivery, or possibly treated in neonatal stage. Late deceleration, the deceleration in supine hypotension, and umbilical cord abnormality will disappear by maternal lateral posture.

Conclusion: There are cases cured by Caesarean delivery, while some abnormalities will be treated without surgery.

https://crimsonpublishers.com/didd/fulltext/DIDD.000513.php

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