Synthesis and Characterization of ZnONPs from Vitis vinifera Peel Extract and Its Antimicrobial Efficacy by E Davida* in Advancements in Bioequivalence & Bioavailability_ Bioequivalence And Bioavailability International Journal
Abstract
Of silver nanoparticles extracellularly. The
biosynthetic methods have been recognized as an alternative to chemical and
physical synthesis, as this biosynthetic
method is economical, ecofriendly, and cost-effective. The present work
exhibited an efficient and low-cost biological approach to synthesize the metal
nanoparticles and provided helpful insight into the development of new
antimicrobial agents with the synergistic enhancement of the antimicrobial mechanism against
pathogenic microorganisms.
A green synthesis of Zinc Oxide nanoparticles
was carried out using Vitis vinifera skin peel extract. Synthesized
nanoparticles were characterized using UV-Vis absorption spectroscopy, DLS,
TEM, FT-IR and XRD studies respectively. UV-Vis absorption spectroscopy of
prepared Zinc Oxide colloidal solution showed absorption maxima at 230nm. TEM
analysis showed average particle size ranging from 0.5-10μm, while XRD confirms
SAED pattern confirmed the crystalline nature of synthesized nanoparticles.
FT-IR analysis revealed that primary and secondary amine groups in combination
with the protein present in the peel extract are responsible for reduction
reaction and also the stabilization of Zno nanoparticles. DLS shows the
particle size of nanoparticles is 64.4nm and has a negative zeta potential of
-34.1mV. Hence from this study we concluded that the nanoparticles synthesized
from Vitis vinifera peel
extract has shown very effective on in-vitro antimicrobial activity (Gram
positive and negative Bacteria, Fungi) using disc diffusion method.
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