Mathematical Theory of Reliability and Aging: A Little Bit
of History and the State of Art by Vitaly K Koltover in Geriatrics Studies
In engineering, reliability is defined as the ability of a device to
perform the preset function for the given time under the given
conditions. The foundations of mathematical theory of reliability were
laid in the 1950s due to the needs of aeronautic machinery, electronics,
problems of communication and management, etc. [13]. Like in
engineering, each and all biological systems are devices constructed to
perform the preset functions according to the information planes, i.e. -
the genetic programs. Biological constructs perform their functions in
the presence of a great number of random factors which disturb all
functional strata, starting from the molecular level of organization and
to ecosystems inclusive. Therefore, similarly to technical devices,
biological constructs are not perfectly reliable in operation, i.e. -
for each and every device normal acts of operations alternate with
stochastic (random) malfunctions or failures.
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