Advances in The Therapy of Depression by Ghassan Haddad in Techniques in Neurosurgery & Neurology: Crimson Publishers_Journal of Neurology Neurosurgery and Psychiatry
Depression
is one of the most common serious medical and psychiatric disorders,
with greater than 200 million adults worldwide suffering from major
depressive disorder (MDD) at any given time, according to a 2003 report
by the World Health Organization titled Investing in Mental Health.
According to the U.S. National Comorbidity Survey Replication published
in 2007, more than 16 million adults in the United States, which
represents approximately 6.7% of itsentire adult population, will suffer
from MDD in a 12-month period. The quest to come up with a superior
antidepressant is in full effect among biotech and pharmaceutical
companies. Although there are some companies that are still tweaking
various formulations of serotonergic, noradrenergic, and dopaminergic substances i.e. triple reuptake inhibitors others are thinking outside the box.
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