Can Blackcurrant (Ribes Nigrum L) Help in Control of Ligneous Conjunctivitis?_Crimson Publisher

Can Blackcurrant (Ribes Nigrum L) Help in Control ofLigneous Conjunctivitis? by Mariana Granito Ponte de Oliveira in Medical & Surgical Ophthalmology Research

Plasminogen is an enzyme that is linked to the dissolution of fibrin, and consequently thrombi. It plays an important role in the recruitment of macrophages during the inflammatory response. Plasminogen deficiency is a rare autosomal recessive disease, which may be heterozygotes asymptomatic or homozygou symptomatics. It can be correlated to appearance of low levels of plasminogen in children, whose both parents have reduced values [1].

The ligneous Conjunctivitis (LC) is the most common presentation of clinical syndromes associated with type I plasminogen deficiency [2,3]. It's a rare pathology and may be more prevalent in areas where consanguinity is more common [1,3]. Its diagnosis is based on clinical, histological and possibly positive family history. Clinical findings are usually: Chronic tearing, conjunctival hyperemia, pseudomembranous lesion in the conjunctiva and/or other mucosal sites of the body, possibly associated with colloid milium or obstructive congenital hydrocephalus. Such membranes are deeply adhered to the conjunctiva of the eyelid, with its free end. Removal tends to cause bleeding because the area is vascularized [4,5].

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