Atypical Presentation of Orbital Natural Killer cell Lymphoma_Crimson Publishers

Atypical Presentation of Orbital Natural Killer cellLymphoma by Brandon Menke in Medical & Surgical Ophthalmology Research

Natural killer (NK)/T-cell lymphoma is a rare primary non- Hodgkin lymphoma. It can be divided into nasal, non-nasal, and aggressive NK leukaemia/lymphoma subtypes [1]. Nasal NK/T cell lymphoma refers to malignancies originating in the nasopharyngeal area, causing destruction of the nasal cavity, paranasal sinuses, orbits, and surrounding structures. Common presenting signs are midline mass with obstruction, nasal bleeding, and perforation of the hard palate [3]. This subtype is more common in Asia and South America and relatively rare in Western countries [2]. The average age of affected patients is 50-60 years old, and it occurs three times more in males than females [3]. Due to its rare incidence and deceiving presentation, it is often misdiagnosed as chronic sinusitis, granuloma, or fungal infection; thus, the final diagnosis and treatments can be delayed.

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