Water borne diseases has been a major public health concern in Nigeria. This study was conducted to identify and evaluate the antibiotic resistivity pattern of faecal coliforms bacteria isolated from River Wudil in Wudil Local Government Area of Kano State, Nigeria. Four (4) water samples from different part of the river were collected for the study. The bacteriological and physicochemical analyses performed were in accordance with standard procedures. Antibiotic susceptibility patterns of the bacterial isolates were determined using modified Kirby Bauer method. The result of the study revealed that the physicochemical properties of the river are within the WHO and NIS standard. The result of microbiological analysis of the River showed that Escherichia coli, Salmonella typhi, Proteus mirabilis, Enterobacter sp. and Klebsiella pneumoneae were identified E. coli, S. typhi and Klebsiella were present in all the four water samples examined. The result of this study also showed that Gentamicin, Ciprofloxacin, Erythromycin and Levifloxacin were 80-90% effective against the tested bacteria isolates. On the other hand, the isolates were 100% resistant to Ampicillin, 80% resistant to Rifampicin and 60% resistant to Chloramphenicol. Statistical analysis of the results showed significant different on the susceptibility of the isolates to the antibiotics used at p< 0.05. The use of the river water for drinking may be hazardous. The study therefore, stresses on the need to control the faecal pollution of the water before use.
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