Celiac Disease and "Idiopathic" Portal Hypertension: A Case Report and Review of Literature - Crimson Publishers
Celiac Disease and "Idiopathic" PortalHypertension: A Case Report and Review of Literature by Khaled Matar in
Gastroenterology: Medicine & Research
Idiopathic Portal hypertension (IPH) is a disorder of
unknown etiology. We are reporting a case of IPH and Celiac disease. A 39-year
old female patient was referred to gastroenterology clinic for diagnostic
work-up of severe pancytopenia, massive splenomegaly and tense ascites.
Diagnosis of IPH was clinically suspected after exclusion of possible causes
that can manifest as portal hypertension. Endoscopy revealed esophageal varices
along with atrophic folds and scalloping in the second part of the duodenum.
Celiac disease was diagnosed based on histopathology findings and strong
serology positivity for anti- tissue transglutaminase IgA. Her symptoms
improved on a gluten-free diet and laboratory tests results improved
considerably with significant reduction of the spleen size and ascites.
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